Dvoje mrtvih od Fajzer vakcine u Italiji

https://newsmondo.it/lecco-uomo-di-52-anni-morto-dopo-vaccino-pfizer/cronaca/?utm_source=welcoming&utm_medium=newsletter&utm_campaign=informazione-indipendente

JA sam primio Astru prvu dozu, druga za 10 tjedana

Ništa loše mi se nije dogodilo

Serbinho-3 wrote:https://newsmondo.it/lecco-uomo-di-52-anni-morto-dopo-vaccino-pfizer/cronaca/?utm_source=welcoming&utm_medium=newsletter&utm_campaign=informazione-indipendente

Rekapitulacija na današnji dan za Italiju!

Umrli: 1  od 11,000,000  Pfizer doza.
Umrli:  1 od 33 zaražena

Ja se u zadnje vrijeme pitam šta je s  ljudima?
Ili su toliko nepismeni ili su jednostavno glupi?
Mesečini da je oboje u pitanju.

Eroo wrote:

Serbinho-3 wrote:https://newsmondo.it/lecco-uomo-di-52-anni-morto-dopo-vaccino-pfizer/cronaca/?utm_source=welcoming&utm_medium=newsletter&utm_campaign=informazione-indipendente

Rekapitulacija na današnji dan za Italiju!

Umrli: 1  od 11,000,000  Pfizer doza.
Umrli:  1 od 33 zaražena

Ja se u zadnje vrijeme pitam šta je s  ljudima?
Ili su toliko nepismeni ili su jednostavno glupi?
Mesečini da je oboje u pitanju.

Da su od Sputnjika umrli, ne bi imao istu teoriju...

Ne treba da se umire od vakcina.

Eroo wrote:

Serbinho-3 wrote:https://newsmondo.it/lecco-uomo-di-52-anni-morto-dopo-vaccino-pfizer/cronaca/?utm_source=welcoming&utm_medium=newsletter&utm_campaign=informazione-indipendente

Rekapitulacija na današnji dan za Italiju!

Umrli: 1  od 11,000,000  Pfizer doza.
Umrli:  1 od 33 zaražena

Ja se u zadnje vrijeme pitam šta je s  ljudima?
Ili su toliko nepismeni ili su jednostavno glupi?
Mesečini da je oboje u pitanju.

Vozi se Ero autocestom i sluša radio. Odjednom prestaje muzika i spiker kaže:
- „ Prekidamo program da vas obavijestimo da neki luđak vozi autocestom u krivom smjeru.“
Ero: „ Šta jedan?! Stotine, stotine!“

Eroo wrote:

Serbinho-3 wrote:https://newsmondo.it/lecco-uomo-di-52-anni-morto-dopo-vaccino-pfizer/cronaca/?utm_source=welcoming&utm_medium=newsletter&utm_campaign=informazione-indipendente

Rekapitulacija na današnji dan za Italiju!

Umrli: 1  od 11,000,000  Pfizer doza.
Umrli:  1 od 33 zaražena

Ja se u zadnje vrijeme pitam šta je s  ljudima?
Ili su toliko nepismeni ili su jednostavno glupi?
Mesečini da je oboje u pitanju.

. Ovo treba slikati čisto da se vidi, ovakvih ti provala si imao na tone

Što se mene tiče budem od nekog zeme riješio potvrdu da sam cijepljen naravno bez da unosim te kemikalije

Serbinho-3 wrote:

Eroo wrote:

Serbinho-3 wrote:https://newsmondo.it/lecco-uomo-di-52-anni-morto-dopo-vaccino-pfizer/cronaca/?utm_source=welcoming&utm_medium=newsletter&utm_campaign=informazione-indipendente

Rekapitulacija na današnji dan za Italiju!

Umrli: 1  od 11,000,000  Pfizer doza.
Umrli:  1 od 33 zaražena

Ja se u zadnje vrijeme pitam šta je s  ljudima?
Ili su toliko nepismeni ili su jednostavno glupi?
Mesečini da je oboje u pitanju.

Da su od Sputnjika umrli, ne bi imao istu teoriju...

Ne treba da se umire od vakcina.

Radi se o eksperimentu. Pribrojiti ćemo na kraju mrtve i neželjene posljedice ( autoimune bolesti i sl. ) nezavisno tijelo će ga ispitati, a ne kompanija koja ga je napravila i onda ćemo reći je li sigurno ili nije. 
Do tada Ero svira qurcu.

AssadNaPodmornici wrote:Što se mene tiče budem od nekog zeme riješio potvrdu da sam cijepljen naravno bez da unosim te kemikalije

Ja imam pravo nju jer sam prebolio, a neću je tražiti iz principa.

Serbinho-3 wrote:

Eroo wrote:

Serbinho-3 wrote:https://newsmondo.it/lecco-uomo-di-52-anni-morto-dopo-vaccino-pfizer/cronaca/?utm_source=welcoming&utm_medium=newsletter&utm_campaign=informazione-indipendente

Rekapitulacija na današnji dan za Italiju!

Umrli: 1  od 11,000,000  Pfizer doza.
Umrli:  1 od 33 zaražena

Ja se u zadnje vrijeme pitam šta je s  ljudima?
Ili su toliko nepismeni ili su jednostavno glupi?
Mesečini da je oboje u pitanju.

Da su od Sputnjika umrli, ne bi imao istu teoriju...

Ne treba da se umire od vakcina.

Od svakog  lijeka možeš umrijeti ako si alergičan na neku snov u lijeku.
U USA  je od  100,000,000 cjepljenih od zaraze coronom umrlo 132 ljudi....1.32/1,000,000.  ....inače 2/100 zaraženih.

mutava baštarda wrote:

Serbinho-3 wrote:

Eroo wrote:

Serbinho-3 wrote:https://newsmondo.it/lecco-uomo-di-52-anni-morto-dopo-vaccino-pfizer/cronaca/?utm_source=welcoming&utm_medium=newsletter&utm_campaign=informazione-indipendente

Rekapitulacija na današnji dan za Italiju!

Umrli: 1  od 11,000,000  Pfizer doza.
Umrli:  1 od 33 zaražena

Ja se u zadnje vrijeme pitam šta je s  ljudima?
Ili su toliko nepismeni ili su jednostavno glupi?
Mesečini da je oboje u pitanju.

Da su od Sputnjika umrli, ne bi imao istu teoriju...

Ne treba da se umire od vakcina.

Radi se o eksperimentu. Pribrojiti ćemo na kraju mrtve i neželjene posljedice ( autoimune bolesti i sl. ) nezavisno tijelo će ga ispitati, a ne kompanija koja ga je napravila i onda ćemo reći je li sigurno ili nije. 
Do tada Ero svira qurcu.

Taman  sam ti mislio reći da uklopiš modul za logično zaključivanje,
ali sam odustao, jer sam logički zaključio da ti to ne posjeduješ.

Eroo wrote:

Serbinho-3 wrote:

Eroo wrote:

Serbinho-3 wrote:https://newsmondo.it/lecco-uomo-di-52-anni-morto-dopo-vaccino-pfizer/cronaca/?utm_source=welcoming&utm_medium=newsletter&utm_campaign=informazione-indipendente

Rekapitulacija na današnji dan za Italiju!

Umrli: 1  od 11,000,000  Pfizer doza.
Umrli:  1 od 33 zaražena

Ja se u zadnje vrijeme pitam šta je s  ljudima?
Ili su toliko nepismeni ili su jednostavno glupi?
Mesečini da je oboje u pitanju.

Da su od Sputnjika umrli, ne bi imao istu teoriju...

Ne treba da se umire od vakcina.

Od svakog  lijeka možeš umrijeti ako si alergičan na neku snov u lijeku.
U USA  je od  100,000,000 cjepljenih od zaraze coronom umrlo 132 ljudi....1.32/1,000,000.  ....inače 2/100 zaraženih.

Umrla s cjepivom, a ne od cjepiva.

mutava baštarda wrote:

Eroo wrote:

Serbinho-3 wrote:

Eroo wrote:

Serbinho-3 wrote:https://newsmondo.it/lecco-uomo-di-52-anni-morto-dopo-vaccino-pfizer/cronaca/?utm_source=welcoming&utm_medium=newsletter&utm_campaign=informazione-indipendente

Rekapitulacija na današnji dan za Italiju!

Umrli: 1  od 11,000,000  Pfizer doza.
Umrli:  1 od 33 zaražena

Ja se u zadnje vrijeme pitam šta je s  ljudima?
Ili su toliko nepismeni ili su jednostavno glupi?
Mesečini da je oboje u pitanju.

Da su od Sputnjika umrli, ne bi imao istu teoriju...

Ne treba da se umire od vakcina.

Od svakog  lijeka možeš umrijeti ako si alergičan na neku snov u lijeku.
U USA  je od  100,000,000 cjepljenih od zaraze coronom umrlo 132 ljudi....1.32/1,000,000.  ....inače 2/100 zaraženih.

Umrla s cjepivom, a ne od cjepiva.

U Hrvatskoj do jučer od corone umrlo 8,026 ljudi, svaki 44.-i zaraženi. Od cjepljenja ni jedan.

Vaccine researcher admits ‘big mistake,’ says spike protein is dangerous ‘toxin’
‘Terrifying’ new research finds vaccine spike protein unexpectedly in bloodstream. The protein is linked to blood clots, heart and brain damage, and potential risks to nursing babies and fertility.
Mon May 31, 2021 - 5:22 pm EST

May 31, 2021 (LifeSiteNews) — New research shows that the coronavirus spike protein from COVID-19 vaccination unexpectedly enters the bloodstream, which is a plausible explanation for thousands of reported side-effects from blood clots and heart disease to brain damage and reproductive issues, a Canadian cancer vaccine researcher said last week.

“We made a big mistake. We didn’t realize it until now,” said Byram Bridle, a viral immunologist and associate professor at University of Guelph, Ontario, in an interview with Alex Pierson last Thursday, in which he warned listeners that his message was “scary.”

“We thought the spike protein was a great target antigen, we never knew the spike protein itself was a toxin and was a pathogenic protein. So by vaccinating people we are inadvertently inoculating them with a toxin,” Bridle said on the show, which is not easily found in a Google search but went viral on the internet this weekend.

Bridle, a vaccine researcher who was awarded a $230,000 government grant last year for research on COVID vaccine development, said that he and a group of international scientists filed a request for information from the Japanese regulatory agency to get access to what’s called the “biodistribution study.”

“It’s the first time ever scientists have been privy to seeing where these messenger RNA [mRNA] vaccines go after vaccination,” said Bridle. “Is it a safe assumption that it stays in the shoulder muscle? The short answer is: absolutely not. It’s very disconcerting.”

Vaccine researchers had assumed that novel mRNA COVID vaccines would behave like “traditional” vaccines and the vaccine spike protein — responsible for infection and its most severe symptoms — would remain mostly in the vaccination site at the shoulder muscle. Instead, the Japanese data showed that the infamous spike protein of the coronavirus gets into the blood where it circulates for several days post-vaccination and then accumulated in organs and tissues including the spleen, bone marrow, the liver, adrenal glands, and in “quite high concentrations” in the ovaries.

“We have known for a long time that the spike protein is a pathogenic protein. It is a toxin. It can cause damage in our body if it gets into circulation,” Bridle said.

The SARS-CoV-2 spike protein is what allows it to infect human cells. Vaccine manufacturers chose to target the unique protein, making cells in the vaccinated person manufacture the protein which would then, in theory, evoke an immune response to the protein, preventing it from infecting cells.

A large number of studies has shown that the most severe effects of SARS-CoV-2, the virus that causes COVID-19, such as blood clotting and bleeding, are due to the effects of the spike protein of the virus itself

“What has been discovered by the scientific community is the spike protein on its own is almost entirely responsible for the damage to the cardiovascular system, if it gets into circulation,” Bridle told listeners.

Lab animals injected with purified spike protein into their bloodstream developed cardiovascular problems, and the spike protein was also demonstrated to cross the blood brain barrier and cause damage to the brain.

A grave mistake, according to Bridle, was the belief that the spike protein would not escape into the blood circulation. “Now, we have clear-cut evidence that the vaccines that make the cells in our deltoid muscles manufacture this protein — that the vaccine itself, plus the protein — gets into blood circulation,” he said.

Bridle cited the recent publication of a peer-reviewed study which detected spike protein in the blood plasma of three of 13 young healthcare workers that had received Moderna’s COVID-19 vaccine. In one of the workers, the spike protein circulated for 29 days.
Effects on heart and brain

Once in circulation, the spike protein can attach to specific ACE2 receptors that are on blood platelets and the cells that line blood vessels. “When that happens it can do one of two things: it can either cause platelets to clump, and that can lead to clotting. That’s exactly why we’ve been seeing clotting disorders associated with these vaccines. It can also lead to bleeding.” Bridle also said the spike protein in circulation would explain recently reported heart problems in youths who had received the shots.

The results of this leaked Pfizer study tracing the biodistribution of the vaccine mRNA are not surprising, “but the implications are terrifying,” Stephanie Seneff, a senior research scientist at Massachusetts Institute of Technology, told LifeSiteNews. “It is now clear” that vaccine content is being delivered to the spleen and the glands, including the ovaries and the adrenal glands.

The Centers for Disease Control and Prevention (CDC) recently announced it was studying reports of “mild” heart conditions following COVID-19 vaccination, and last week 18 teenagers in the state of Connecticut alone were hospitalized for heart problems that developed shortly after they took COVID-19 vaccines.

AstraZeneca’s vaccine was halted in a number of countries and is no longer recommended for younger people because of its link to life-threatening and fatal blood clots, but mRNA COVID vaccines have been linked to hundreds of reports of blood clotting events as well.

FDA warned of spike protein danger

Pediatric rheumatologist J. Patrick Whelan had warned a vaccine advisory committee of the Food and Drug Administration of the potential for the spike protein in COVID vaccines to cause microvascular damage causing damage to the liver, heart, and brain in “ways that were not assessed in the safety trials.”

While Whelan did not dispute the value of a coronavirus vaccine that worked to stop transmission of the disease (which no COVID vaccine in circulation has been demonstrated to do), he said, “it would be vastly worse if hundreds of millions of people were to suffer long-lasting or even permanent damage to their brain or heart microvasculature as a result of failing to appreciate in the short-term an unintended effect of full-length spike protein-based vaccines on other organs.”

Vaccine-associated spike protein in blood circulation could explain myriad reported adverse events from COVID vaccines, including the 4,000 deaths to date, and nearly 15,000 hospitalizations, reported to the U.S. government’s Vaccine Adverse Event Reporting System (VAERS) as of May 21, 2021. Because it is a passive reporting system, these reports are likely only the tip of an iceberg of adverse events since a Harvard Pilgrim Healthcare study found that less than one percent of side-effects that physicians should report in patients following vaccination are in fact reported to VAERS.
Nursing babies, children and youths, frail, most at risk

Bridle said the discovery of vaccine-induced spike protein in blood circulation would have implications for blood donation programs. “We don’t want transfer of these pathogenic spike proteins to fragile patients who are being transfused with that blood,” he said.

https://www.lifesitenews.com/news/vaccine-researcher-admits-big-mistake-says-spike-protein-is-dangerous-toxin

The spike proteins of Covid-19 have a strong neurotoxic effect with severe consequences

The following is what Brazilian researchers came up with when studying tadpoles. On the one hand, the protein fragments that make up the spike proteins increased oxidative stress, and on the other hand, they increased the activity of the so-called acetylcholinesterase, thereby excessively degrading acetylcholine from the nervous system and other cells. (1)

The latter has serious consequences. If the acetylcholine in the heart decreases, its effects are permanently damaging to the heart and it can promote the development of heart failure. This may be indicated by an increase in heart rate, which is also quite common in Covid patients with mild symptoms.

Decreased acetylcholine in the heart may be accompanied by the weakening of the parasympathetic nervous system and a jump in heart rate. (2) (3) Decreased acetylcholine and damage to the acetylcholine signaling system also have serious consequences in the central nervous system.

It reduces the function of the neural inflammatory pathway, the cholinergic anti-inflammatory pathway, and promotes the development of a cytokine storm and the development of a life-threatening condition. (4)

In those with pre-existing brain damage to the acetylcholine signaling system, such as at patients with Alzheimer’s, impaired heart rate variability also indicates dysfunction of the anti-inflammatory cholinergic system and thus the coronavirus caused disease is more prone to the development of cytokine storms. (5) Scientists, therefore, recommend activating the vagus nerve and strengthening the cholinergic anti-inflammatory pathway in the fight against coronavirus. (6) (7) It has a good reason that the infection becomes critical and a cytokine storm occurs in those who have previously shown a significant drop in heart rate variability (HRV), as this predicts a weakening of the cholinergic anti-inflammatory pathway. (8)

In my opinion, it is shocking that, as a primary drug defense against coronavirus, immunization therapies based on the toxic proteins of spike protein are being introduced and injected into the bloodstream. This is certainly based on a disregard for the existing spike protein literature. The neurotoxic effect of spike protein may be significantly enhanced by the possible aluminum content of vaccines, such as for EpiVacCorona rated as 100% effective. (13) The use of proinsulin c-peptide may be a promising therapeutic intervention for several reasons. On the one hand, it can generally reduce oxidative stress. (9) (10) (11) On the other hand, it can effectively strengthen HRV and thus the cholinergic anti-inflammatory pathway. (12)

https://sdnn70.com/en/the-spike-proteins-of-covid-19-have-a-strong-neurotoxic-effect-with-severe-consequences/

Pfizer Confirms COVID-Vaccinated People Can ‘Shed’ Spike Proteins And Harm The Unvaccinated

A new study has confirmed that people who have been vaccinated against COVID produce excessive spike proteins that are capable of passing the Blood Brain Barrier causing irreparable damage to the brain — and Pfizer’s own documents warn that vaccinated people actually shed these excessive spike proteins putting the unvaccinated at risk for harm:

https://www.biorxiv.org/content/biorxiv/early/2020/12/04/2020.12.04.409144.full.pdf

So Pfizer’s own internal report (on page 69) warns health care workers about being exposed to people who have been vaccinated — which is rather ironic considering most health care workers are required to be vaccinated themselves.

Anyone walking in to a hospital or doctor’s office will be exposed to the spike proteins being shed by virtually the entire staff of workers — but the concentrations will be low compared to what is in the blood streams of the vaccinated.

Of course, the amount of spike proteins you could actually breathe in is miniscule compared to the amount that these vaccines are programming vaccinated people’s bodies to manufacture — non-stop 24/7.

A recent study confirms that the spike proteins produced by the mRNA vaccines can indeed cause serious health problems as they continuously build up in the vaccinated.

As literally trillions of these spike proteins build up and overwhelm your body, your internal organs will begun to shut down and your brain will stop functioning — which is why a U.K. government report is predicting a huge percentage of doubly vaccinated people will be dying in the coming “Third Wave” of the fake pandemic.

This coming massive death toll will, of course, be blamed on new, exotic-sound virus “variant” — or better yet, “scare-iants” — and the “selfish unvaccinated.”

Needless to say, it would behoove everyone who is unvaccinated to avoid extended exposure to the vaccinated, especially in confined spaces.

COVID-19 RNA Based Vaccines and the Risk of Prion Disease

https://scivisionpub.com/pdfs/covid19-rna-based-vaccines-and-the-risk-of-prion-disease-1503.pdf

https://media.tghn.org/medialibrary/2020/11/C4591001_Clinical_Protocol_Nov2020_Pfizer_BioNTech.pdf

https://christiansfortruth.com/confirmed-covid-vaccinated-people-can-shed-spike-proteins-and-harm-the-unvaccinated/

Eroo wrote:

mutava baštarda wrote:

Eroo wrote:

Serbinho-3 wrote:

Eroo wrote:

Serbinho-3 wrote:https://newsmondo.it/lecco-uomo-di-52-anni-morto-dopo-vaccino-pfizer/cronaca/?utm_source=welcoming&utm_medium=newsletter&utm_campaign=informazione-indipendente

Rekapitulacija na današnji dan za Italiju!

Umrli: 1  od 11,000,000  Pfizer doza.
Umrli:  1 od 33 zaražena

Ja se u zadnje vrijeme pitam šta je s  ljudima?
Ili su toliko nepismeni ili su jednostavno glupi?
Mesečini da je oboje u pitanju.

Da su od Sputnjika umrli, ne bi imao istu teoriju...

Ne treba da se umire od vakcina.

Od svakog  lijeka možeš umrijeti ako si alergičan na neku snov u lijeku.
U USA  je od  100,000,000 cjepljenih od zaraze coronom umrlo 132 ljudi....1.32/1,000,000.  ....inače 2/100 zaraženih.

Umrla s cjepivom, a ne od cjepiva.

U Hrvatskoj do jučer od corone umrlo 8,026 ljudi, svaki 44.-i zaraženi. Od cjepljenja ni jedan.

Umire se od korone...  A kad je cijepivo u pitanju onda se umire zaštićeno.

COVID-19 RNA Based Vaccines and the Risk of Prion Disease

Results

Analysis of the Pfizer vaccine against COVID-19 identified two potential risk factors for inducing prion disease is humans. The RNA sequence in the vaccine [3] contains sequences believed to induce TDP-43 and FUS to aggregate in their prion based conformation leading to the development of common neurodegerative diseases. In  particular  it  has  been  shown  that  RNA  sequences  GGUA  [4],  UG rich sequences [5], UG tandem repeats [6], and G Quadruplex sequences  [7],  have  increased  affinity  to  bind  TDP-43  and  or FUS  and  may  cause  TDP-43  or  FUS  to  take  their  pathologic  configurations in the cytoplasm. In the current analysis a total of sixteen UG tandem repeats (ΨGΨG) were identified and additional UG (ΨG) rich sequences were identified. Two GGΨA sequences were  found.  G  Quadruplex  sequences  are  possibly  present  but  sophisticated computer programs are needed to verify these.The  spike  protein  encoded  by  the  vaccine  binds  angiotensin  converting  enzyme  2  (ACE2),  an  enzyme  which  contains  zinc  molecules  [8].  The  binding  of  spike  protein  to  ACE2  has  the  potential to release the zinc molecule, an ion that causes TDP-43 to assume its pathologic prion transformation [9].

Discussion

There  is  an  old  saying  in  medicine  that  “the  cure  may  be  worse  than  the  disease.”  The  phrase  can  be  applied  to  vaccines.  In  the  current  paper  the  concern  is  raised  that  the  RNA  based  COVID  vaccines  have  the  potential  to  cause  more  disease  than  the  epidemic  of  COVID-19.  This  paper  focuses  on  a  novel  potential  adverse  event  mechanism  causing  prion  disease  which  could  be  even  more  common  and  debilitating  than  the  viral  infection  the  vaccine  is  designed  to  prevent.  While  this  paper  focuses  on  one  potential  adverse  event  there  are  multiple  other  potential  fatal  adverse events as discussed below.Over the last two decades there has been a concern among certain scientists that prions could be used as bioweapons. More recently there  has  been  a  concern  that  ubiquitous  intracellular  molecules  could  be  activated  to  cause  prion  disease  including  Alzheimer’s  disease, ALS and other neurodegenerative diseases. This concern originates  due  to  potential  for  misuse  of  research  data  on  the  mechanisms by which certain RNA binding proteins like TDP-43, FUS  and  others  can  be  activated  to  form  disease  causing  prions.  The  fact  that  this  research,  which  could  be  used  for  bioweapons  development, is funded by private organizations including the Bill and  Melinda  Gates  Foundation,  and  Ellison  Medical  Foundation  [2]  without  national/international  oversight  is  also  a  concern.  In  the  past,  for  example,  there  were  prohibitions  for  publishing  information pertaining to construction of nuclear bombs.

https://scivisionpub.com/pdfs/covid19-rna-based-vaccines-and-the-risk-of-prion-disease-1503.pdf

The novel coronavirus’ spike protein plays additional key role in illness

Salk researchers and collaborators show how the protein damages cells, confirming COVID-19 as a primarily vascular disease

LA JOLLA—Scientists have known for a while that SARS-CoV-2’s distinctive “spike” proteins help the virus infect its host by latching on to healthy cells. Now, a major new study shows that the virus spike proteins (which behave very differently than those safely encoded by vaccines) also play a key role in the disease itself.

The paper, published on April 30, 2021, in Circulation Research, also shows conclusively that COVID-19 is a vascular disease, demonstrating exactly how the SARS-CoV-2 virus damages and attacks the vascular system on a cellular level. The findings help explain COVID-19’s wide variety of seemingly unconnected complications, and could open the door for new research into more effective therapies.

“A lot of people think of it as a respiratory disease, but it’s really a vascular disease,” says Assistant Research Professor Uri Manor, who is co-senior author of the study. “That could explain why some people have strokes, and why some people have issues in other parts of the body. The commonality between them is that they all have vascular underpinnings.”

Salk researchers collaborated with scientists at the University of California San Diego on the paper, including co-first author Jiao Zhang and co-senior author John Shyy, among others.

While the findings themselves aren’t entirely a surprise, the paper provides clear confirmation and a detailed explanation of the mechanism through which the protein damages vascular cells for the first time. There’s been a growing consensus that SARS-CoV-2 affects the vascular system, but exactly how it did so was not understood. Similarly, scientists studying other coronaviruses have long suspected that the spike protein contributed to damaging vascular endothelial cells, but this is the first time the process has been documented.

In the new study, the researchers created a “pseudovirus” that was surrounded by SARS-CoV-2 classic crown of spike proteins, but did not contain any actual virus. Exposure to this pseudovirus resulted in damage to the lungs and arteries of an animal model—proving that the spike protein alone was enough to cause disease. Tissue samples showed inflammation in endothelial cells lining the pulmonary artery walls.

The team then replicated this process in the lab, exposing healthy endothelial cells (which line arteries) to the spike protein. They showed that the spike protein damaged the cells by binding ACE2. This binding disrupted ACE2’s molecular signaling to mitochondria (organelles that generate energy for cells), causing the mitochondria to become damaged and fragmented.

Previous studies have shown a similar effect when cells were exposed to the SARS-CoV-2 virus, but this is the first study to show that the damage occurs when cells are exposed to the spike protein on its own.

“If you remove the replicating capabilities of the virus, it still has a major damaging effect on the vascular cells, simply by virtue of its ability to bind to this ACE2 receptor, the S protein receptor, now famous thanks to COVID,” Manor explains. “Further studies with mutant spike proteins will also provide new insight towards the infectivity and severity of mutant SARS CoV-2 viruses.”

The researchers next hope to take a closer look at the mechanism by which the disrupted ACE2 protein damages mitochondria and causes them to change shape.

https://www.salk.edu/news-release/the-novel-coronavirus-spike-protein-plays-additional-key-role-in-illness/

Neće Srbe i Vlaje nitko cijepiti, trave babe Mande i Urošovo proročanstvo se ostvaruju.