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Južna Afrika: Oxfordsko cjepivo je na razini placeba
by Hektorović 7/2/2021, 21:42
https://www.nytimes.com/live/2021/02/07/world/covid-19-coronavirus?campaign_id=60&emc=edit_na_20210207&instance_id=0&nl=breaking-news&ref=cta®i_id=124640758&segment_id=51190&user_id=3e7eb6aa62cf0b7e60314ade7b55f233#south-africa-says-astrazenecas-vaccine-is-not-very-effective-at-stopping-a-variant-from-causing-illness
South Africa says AstraZeneca’s vaccine is not very effective at stopping a variant from causing illness.
Paramedics transported a patient in Pretoria using an isolation chamber. Officials said that new data shows that the AstraZeneca-Oxford vaccine does not work well against the virus variant first identified there.Phill Magakoe/Agence France-Presse — Getty Images
South Africa halted use of the AstraZeneca-Oxford coronavirus vaccine on Sunday after evidence emerged that the vaccine did not protect clinical-trial participants from mild or moderate illness caused by the more contagious virus variant that was first seen there.
The findings were a devastating blow to the country’s efforts to combat the pandemic.
Scientists in South Africa said on Sunday that a similar problem held among people who had been infected by earlier versions of the coronavirus: the immunity they acquired naturally did not appear to protect them from mild or moderate cases when reinfected by the variant, known as B.1.351.
The developments, coming nearly a week after a million doses of the AstraZeneca-Oxford vaccine arrived in South Africa, were an enormous setback for the country, where more than 46,000 people are known to have died from the virus. And they were another sign of the dangers posed by new mutations in the coronavirus. The B.1.351 variant has already spread to at least 32 countries, including the United States.
It was not clear from the studies outlined by South African scientists on Sunday whether the AstraZeneca-Oxford vaccine protected against severe disease from the B.1.351 variant.
The clinical trial participants who were evaluated were relatively young and unlikely to become severely ill, making it impossible for the scientists to determine if the variant interfered with the AstraZeneca-Oxford vaccine’s ability to protect against severe Covid-19, hospitalizations, or deaths.
However, based on the immune responses detected in blood samples from people who were given the vaccine, the scientists said they believed that the vaccine could yet protect against more severe cases.
If further studies show that it does, South African health officials said on Sunday that they would consider resuming use of the AstraZeneca-Oxford vaccine.
Even so, the fact that it showed minimal efficacy in preventing mild and moderate cases of the new variant added to the mounting evidence that B.1.351 makes current vaccines less effective. These research findings have not been published in a scientific journal.
Pfizer and Moderna have both said that preliminary laboratory studies indicate that their vaccines, while still protective, are less effective against B.1.351. Novavax and Johnson & Johnson have also sequenced test samples from their clinical trial participants in South Africa, where B.1.351 caused the vast majority of cases — and both reported lower efficacy there than in the United States.
“These results are very much a reality check,” Shabir Madhi, a virologist at University of the Witwatersrand who ran the AstraZeneca-Oxford vaccine trial in South Africa, said of the findings released on Sunday.
The pause in the country’s rollout of the AstraZeneca-Oxford vaccine means that the first shipments will now be put in warehouses. Instead, South African health officials said they would inoculate health workers in the coming weeks with the Johnson & Johnson vaccine, which has strong efficacy in preventing severe cases and hospitalizations caused by the new variant.
Johnson & Johnson has applied for an emergency use authorization in South Africa. But health officials there indicated that even before it is authorized, some health workers could be given the vaccine as part of an ongoing trial.
In the AstraZeneca-Oxford trial in South Africa, roughly 2,000 participants were given either two doses of the vaccine or placebo shots.
There was virtually no difference in the numbers of people in the vaccine and placebo groups who were infected with B.1.351, suggesting that the vaccine did little to protect against the new variant. Nineteen of the 748 people in the group that was given the vaccine were infected with the new variant, compared to 20 out of 714 people in the group that was given a placebo.
That equates to a vaccine efficacy of 10 percent, though the scientists did not have enough statistical confidence to know for sure whether that figure would hold among more people.
South Africa says AstraZeneca’s vaccine is not very effective at stopping a variant from causing illness.
Paramedics transported a patient in Pretoria using an isolation chamber. Officials said that new data shows that the AstraZeneca-Oxford vaccine does not work well against the virus variant first identified there.Phill Magakoe/Agence France-Presse — Getty Images
South Africa halted use of the AstraZeneca-Oxford coronavirus vaccine on Sunday after evidence emerged that the vaccine did not protect clinical-trial participants from mild or moderate illness caused by the more contagious virus variant that was first seen there.
The findings were a devastating blow to the country’s efforts to combat the pandemic.
Scientists in South Africa said on Sunday that a similar problem held among people who had been infected by earlier versions of the coronavirus: the immunity they acquired naturally did not appear to protect them from mild or moderate cases when reinfected by the variant, known as B.1.351.
The developments, coming nearly a week after a million doses of the AstraZeneca-Oxford vaccine arrived in South Africa, were an enormous setback for the country, where more than 46,000 people are known to have died from the virus. And they were another sign of the dangers posed by new mutations in the coronavirus. The B.1.351 variant has already spread to at least 32 countries, including the United States.
It was not clear from the studies outlined by South African scientists on Sunday whether the AstraZeneca-Oxford vaccine protected against severe disease from the B.1.351 variant.
The clinical trial participants who were evaluated were relatively young and unlikely to become severely ill, making it impossible for the scientists to determine if the variant interfered with the AstraZeneca-Oxford vaccine’s ability to protect against severe Covid-19, hospitalizations, or deaths.
However, based on the immune responses detected in blood samples from people who were given the vaccine, the scientists said they believed that the vaccine could yet protect against more severe cases.
If further studies show that it does, South African health officials said on Sunday that they would consider resuming use of the AstraZeneca-Oxford vaccine.
Even so, the fact that it showed minimal efficacy in preventing mild and moderate cases of the new variant added to the mounting evidence that B.1.351 makes current vaccines less effective. These research findings have not been published in a scientific journal.
Pfizer and Moderna have both said that preliminary laboratory studies indicate that their vaccines, while still protective, are less effective against B.1.351. Novavax and Johnson & Johnson have also sequenced test samples from their clinical trial participants in South Africa, where B.1.351 caused the vast majority of cases — and both reported lower efficacy there than in the United States.
“These results are very much a reality check,” Shabir Madhi, a virologist at University of the Witwatersrand who ran the AstraZeneca-Oxford vaccine trial in South Africa, said of the findings released on Sunday.
The pause in the country’s rollout of the AstraZeneca-Oxford vaccine means that the first shipments will now be put in warehouses. Instead, South African health officials said they would inoculate health workers in the coming weeks with the Johnson & Johnson vaccine, which has strong efficacy in preventing severe cases and hospitalizations caused by the new variant.
Johnson & Johnson has applied for an emergency use authorization in South Africa. But health officials there indicated that even before it is authorized, some health workers could be given the vaccine as part of an ongoing trial.
In the AstraZeneca-Oxford trial in South Africa, roughly 2,000 participants were given either two doses of the vaccine or placebo shots.
There was virtually no difference in the numbers of people in the vaccine and placebo groups who were infected with B.1.351, suggesting that the vaccine did little to protect against the new variant. Nineteen of the 748 people in the group that was given the vaccine were infected with the new variant, compared to 20 out of 714 people in the group that was given a placebo.
That equates to a vaccine efficacy of 10 percent, though the scientists did not have enough statistical confidence to know for sure whether that figure would hold among more people.
Hektorović- Posts : 26373
2018-04-10
Re: Južna Afrika: Oxfordsko cjepivo je na razini placeba
by RayMabus 7/2/2021, 21:46
To cjepivo je žešći promašaj. To nama Plenkovic oće uvalit a ne valja ništa.
https://slobodnadalmacija.hr/vijesti/hrvatska/umirovljenici-ljutiti-zbog-cijepljenja-astrazenecom-salju-nas-u-ambulante-a-hladnokrvno-tvrde-da-nema-dovoljno-podataka-o-ucinkovitosti-cjepiva-na-nama-starijima-1076065
https://slobodnadalmacija.hr/vijesti/hrvatska/umirovljenici-ljutiti-zbog-cijepljenja-astrazenecom-salju-nas-u-ambulante-a-hladnokrvno-tvrde-da-nema-dovoljno-podataka-o-ucinkovitosti-cjepiva-na-nama-starijima-1076065
RayMabus- Posts : 176040
2014-04-11
Re: Južna Afrika: Oxfordsko cjepivo je na razini placeba
by Hektorović 7/2/2021, 21:50
RayMabus wrote:To cjepivo je žešći promašaj. To nama Plenkovic oće uvalit a ne valja ništa.
https://slobodnadalmacija.hr/vijesti/hrvatska/umirovljenici-ljutiti-zbog-cijepljenja-astrazenecom-salju-nas-u-ambulante-a-hladnokrvno-tvrde-da-nema-dovoljno-podataka-o-ucinkovitosti-cjepiva-na-nama-starijima-1076065
PR za smirivanje naroda...
Hektorović- Posts : 26373
2018-04-10
Re: Južna Afrika: Oxfordsko cjepivo je na razini placeba
by RayMabus 7/2/2021, 21:53
Stavili malo mlake vodice u bočicu i rekli evo cjepivo a ono nema nikakvi učinak
https://balkans.aljazeera.net/videos/2021/02/07/astrazeneca-prilagodava-vakcinu-novom-juznoafrickom-soju
https://balkans.aljazeera.net/videos/2021/02/07/astrazeneca-prilagodava-vakcinu-novom-juznoafrickom-soju
RayMabus- Posts : 176040
2014-04-11
Re: Južna Afrika: Oxfordsko cjepivo je na razini placeba
by Hektorović 7/2/2021, 21:59
Južna Afrika stopirala cijepljenje AstraZenecom jer slabo štiti protiv novog soja
prije 3 minute
Foto: Epa
JUŽNA AFRIKA obustavit će upotrebu cjepiva protiv covida-19 kompanije AstraZenece unutar svog programa cijepljenja nakon što su podaci pokazali da pruža minimalnu zaštitu od blage do umjerene infekcije uzrokovane dominantnom varijantom koronavirusa u toj zemlji.
Ministar zdravstva Zweli Mkhize rekao je danas da će vlada, nakon razočaravajućih rezultata u ispitivanja koje je provelo Sveučilište Witwatersrand, pričekati savjete nadležnih znanstvenika o tome kako najbolje postupiti s već dobivenim dozama cjepiva, piše Reuters.
Umjesto toga će ih unutar sljedećih nekoliko tjedana cijepiti cjepivima kompanija Johnson & Johnson i Pfizer, a stručnjaci će razmotriti što će učiniti s već pristiglim dozama cjepiva AstraZenece.
"Što to znači za naš program cijepljenja za koji smo rekli da će započeti u veljači? Odgovor je da će se on nastaviti. Očekujemo da ćemo od sljedećeg tjedna pa do narednih četiri tjedana dobiti cjepiva J&J i Pfizer. Dakle, ona će biti dostupna zdravstvenim djelatnicima", rekao je Mkhize.
"Cjepivo AstraZenece ćemo sačuvati sve dok stručnjaci ne odluče što s njime dalje učiniti", dodao je.
prije 3 minute
Foto: Epa
JUŽNA AFRIKA obustavit će upotrebu cjepiva protiv covida-19 kompanije AstraZenece unutar svog programa cijepljenja nakon što su podaci pokazali da pruža minimalnu zaštitu od blage do umjerene infekcije uzrokovane dominantnom varijantom koronavirusa u toj zemlji.
Ministar zdravstva Zweli Mkhize rekao je danas da će vlada, nakon razočaravajućih rezultata u ispitivanja koje je provelo Sveučilište Witwatersrand, pričekati savjete nadležnih znanstvenika o tome kako najbolje postupiti s već dobivenim dozama cjepiva, piše Reuters.
Koristit će druga cjepiva
Južna Afrika je u ponedjeljak primila milijun doza AstraZenecinog cjepiva koje je proizvedeno u Indiji, a vlasti su njime prvo namjeravale cijepiti zdravstvene djelatnike.Umjesto toga će ih unutar sljedećih nekoliko tjedana cijepiti cjepivima kompanija Johnson & Johnson i Pfizer, a stručnjaci će razmotriti što će učiniti s već pristiglim dozama cjepiva AstraZenece.
"Što to znači za naš program cijepljenja za koji smo rekli da će započeti u veljači? Odgovor je da će se on nastaviti. Očekujemo da ćemo od sljedećeg tjedna pa do narednih četiri tjedana dobiti cjepiva J&J i Pfizer. Dakle, ona će biti dostupna zdravstvenim djelatnicima", rekao je Mkhize.
"Cjepivo AstraZenece ćemo sačuvati sve dok stručnjaci ne odluče što s njime dalje učiniti", dodao je.
Hektorović- Posts : 26373
2018-04-10
Re: Južna Afrika: Oxfordsko cjepivo je na razini placeba
by RayMabus 7/2/2021, 22:02
I šta će oni sad u Velikoj Britaniji ? Oni su tamo cijepili 11 miljona ljudi šta je 16% populacije upravo s tin cjepivon i sad će opet morat ponovit sve jer ne štiti od tog južnoafričkog soja virusa.
E svašta.
E svašta.
RayMabus- Posts : 176040
2014-04-11
Re: Južna Afrika: Oxfordsko cjepivo je na razini placeba
by RayMabus 7/2/2021, 22:21
Ovi kod nas na vlasti samo pričaju o spašavanju turističke sezone. Izgleda da im je to jedino i bitno u cijeloj priči.
https://slobodnadalmacija.hr/vijesti/hrvatska/markotic-starijima-se-bolje-cijepiti-i-astrazenecinim-cjepivom-nego-ne-uopce-regionalni-ce-stozeri-uskoro-sami-moci-donositi-svoje-odluke-1076152
Alo ba , to cjepivo ne funkcionira.
https://slobodnadalmacija.hr/vijesti/hrvatska/markotic-starijima-se-bolje-cijepiti-i-astrazenecinim-cjepivom-nego-ne-uopce-regionalni-ce-stozeri-uskoro-sami-moci-donositi-svoje-odluke-1076152
Alo ba , to cjepivo ne funkcionira.
RayMabus- Posts : 176040
2014-04-11
Re: Južna Afrika: Oxfordsko cjepivo je na razini placeba
by kaya 7/2/2021, 22:25
Mi smo njihovi taoci izgleda. Zatvorili lokale, cijepivo nisu nabavili, ne brani bitangama nitko naručiti rusko cijepivo, dali bi njima rusi al oni čekaju merkelicu i da čekamo doma do sezone da malo napune proračun.RayMabus wrote:Ovi kod nas na vlasti samo pričaju o spašavanju turističke sezone. Izgleda da im je to jedino i bitno u cijeloj priči.
https://slobodnadalmacija.hr/vijesti/hrvatska/markotic-starijima-se-bolje-cijepiti-i-astrazenecinim-cjepivom-nego-ne-uopce-regionalni-ce-stozeri-uskoro-sami-moci-donositi-svoje-odluke-1076152
Alo ba , to cjepivo ne funkcionira.
Nevjerojatno..
kaya- Posts : 31419
2015-08-15
Re: Južna Afrika: Oxfordsko cjepivo je na razini placeba
by RayMabus 7/2/2021, 22:33
Nije to ni najgora stvar u svemu tome nego skoro svi uključujući Njemačku i Francusku su objavili da neće s time cijepit starije od 65 godina a jedino u nas to nema problema.
Izgleda da Plenkovic misli da ljudi ne čitaju novine i da je on jedini izvor informacija.
On je skroz maka čovik na mozak. Njemu nisu sve na broju.
Izgleda da Plenkovic misli da ljudi ne čitaju novine i da je on jedini izvor informacija.
On je skroz maka čovik na mozak. Njemu nisu sve na broju.
RayMabus- Posts : 176040
2014-04-11
Re: Južna Afrika: Oxfordsko cjepivo je na razini placeba
by Guest 7/2/2021, 22:50
RayMabus wrote:I šta će oni sad u Velikoj Britaniji ? Oni su tamo cijepili 11 miljona ljudi šta je 16% populacije upravo s tin cjepivon i sad će opet morat ponovit sve jer ne štiti od tog južnoafričkog soja virusa.
E svašta.
to je loša vijest jer sva ta cjepiva su neučikovita za južnoafrički soj virusa a možda još i neki drugi soj.
ajde jovo nanovo radi novo cjepivo kao za gripu.
Guest- Guest
Re: Južna Afrika: Oxfordsko cjepivo je na razini placeba
by Guest 7/2/2021, 22:52
kaya wrote:Mi smo njihovi taoci izgleda. Zatvorili lokale, cijepivo nisu nabavili, ne brani bitangama nitko naručiti rusko cijepivo, dali bi njima rusi al oni čekaju merkelicu i da čekamo doma do sezone da malo napune proračun.RayMabus wrote:Ovi kod nas na vlasti samo pričaju o spašavanju turističke sezone. Izgleda da im je to jedino i bitno u cijeloj priči.
https://slobodnadalmacija.hr/vijesti/hrvatska/markotic-starijima-se-bolje-cijepiti-i-astrazenecinim-cjepivom-nego-ne-uopce-regionalni-ce-stozeri-uskoro-sami-moci-donositi-svoje-odluke-1076152
Alo ba , to cjepivo ne funkcionira.
Nevjerojatno..
pridružujem se. treba tu ekipu psihopata streljati inače će nas oni potamaniti više nego virus.
Guest- Guest
Re: Južna Afrika: Oxfordsko cjepivo je na razini placeba
by vuksadinare 8/2/2021, 01:06
Dobro jutro..od kad ja govorim da su cjepiva buckuris za debelu zaradu..ko oni kaj su prodavali 'lijek za sto bolesti' za sto dolara..na divljem zapadu..'lijeci sve celavost,apetit,zubobolju,grlobolju"
vuksadinare- Posts : 99130
2015-09-08
Re: Južna Afrika: Oxfordsko cjepivo je na razini placeba
by Hektorović 8/2/2021, 13:42
kaya wrote:Mi smo njihovi taoci izgleda. Zatvorili lokale, cijepivo nisu nabavili, ne brani bitangama nitko naručiti rusko cijepivo, dali bi njima rusi al oni čekaju merkelicu i da čekamo doma do sezone da malo napune proračun.RayMabus wrote:Ovi kod nas na vlasti samo pričaju o spašavanju turističke sezone. Izgleda da im je to jedino i bitno u cijeloj priči.
https://slobodnadalmacija.hr/vijesti/hrvatska/markotic-starijima-se-bolje-cijepiti-i-astrazenecinim-cjepivom-nego-ne-uopce-regionalni-ce-stozeri-uskoro-sami-moci-donositi-svoje-odluke-1076152
Alo ba , to cjepivo ne funkcionira.
Nevjerojatno..
Malo su se preračunali...
A tek u ove krajeve stižu nove mutacije, koje zaobilaze obranu nastalu prijašnjim kontaktom sa virusom
Hektorović- Posts : 26373
2018-04-10
Re: Južna Afrika: Oxfordsko cjepivo je na razini placeba
by Ringo10 8/2/2021, 15:12
Saaamo zaaaaapadno cjepivo...Samo zaaaapadno
Pa jesu li Hrvati dio Zaaaapadne uljudbe ili nisu
Pa jesu li Hrvati dio Zaaaapadne uljudbe ili nisu
Ringo10- Posts : 21562
2015-09-24
Re: Južna Afrika: Oxfordsko cjepivo je na razini placeba
by kaya 8/2/2021, 16:43
Aha a to su ono nama nabavili jel?
O pička im materina..
O pička im materina..
kaya- Posts : 31419
2015-08-15
Re: Južna Afrika: Oxfordsko cjepivo je na razini placeba
by Hektorović 8/2/2021, 20:31
kaya wrote:Aha a to su ono nama nabavili jel?
O pička im materina..
Ovoga najviše
Capak je na konferenciji za novinare Nacionalnog stožera civilne zaštite rekao da je EU otvorila pregovore sa šest proizvođača u prvoj fazi, a prvi sporazum koji je Hrvatska dobila na uvid bio je onaj AstraZenece.
Od tog je proizvođača naručeno 3,6 milijuna doza cjepiva, ali smo zbog golemog interesa drugih zemalja EU-a dobili 2,7 milijuna doza, pa je ostalih 900.000 doza naručeno od Johnson&Johnsona.
Nakon toga po milijun doza naručen je od Pfizera i Moderne, a 300.000 doza od CureVaca.
Hektorović- Posts : 26373
2018-04-10
Re: Južna Afrika: Oxfordsko cjepivo je na razini placeba
by Hektorović 8/2/2021, 20:35
Hektorović wrote:ostalih 900.000 doza naručeno od Johnson&Johnsona.
Johnson & Johnson’s coronavirus vaccine has shown an overall 66 per cent efficacy rate at preventing moderate and severe Covid-19, although trial results indicate it is less effective against the virus variant first discovered in South Africa.
https://www.ft.com/content/d05c7c57-da11-42a1-aa33-b66052c904ac
[size=33]Johnson & Johnson’s Vaccine Offers Strong Protection but Fuels Concern About Variants[/size]
The vaccine’s efficacy rate dropped from 72 percent in the United States to just 57 percent in South Africa, where a highly contagious variant is driving most cases.
https://www.nytimes.com/2021/01/29/health/covid-vaccine-johnson-and-johnson-variants.html
Hektorović- Posts : 26373
2018-04-10
Re: Južna Afrika: Oxfordsko cjepivo je na razini placeba
by AssadNaPodmornici 8/2/2021, 20:54
srečno svima koji se cijepe..
_________________
May Allah destroy Australia
AssadNaPodmornici- Posts : 20964
2018-06-14
Re: Južna Afrika: Oxfordsko cjepivo je na razini placeba
by kaya 8/2/2021, 21:01
Pa da, dobili cijepivo koje ne funkcionira, i sad moramo sjediti doma do sezone da zdipe lovu i onda će nas opet zatvoriti.Hektorović wrote:kaya wrote:Aha a to su ono nama nabavili jel?
O pička im materina..
Ovoga najviše
[size=63]Capak je na konferenciji za novinare Nacionalnog stožera civilne zaštite rekao da je EU otvorila pregovore sa šest proizvođača u prvoj fazi, a prvi sporazum koji je Hrvatska dobila na uvid bio je onaj AstraZenece.[/size]
[size=63]Od tog je proizvođača naručeno 3,6 milijuna doza cjepiva, ali smo zbog golemog interesa drugih zemalja EU-a dobili 2,7 milijuna doza, pa je ostalih 900.000 doza naručeno od Johnson&Johnsona.[/size]
[size=63]Nakon toga po milijun doza naručen je od Pfizera i Moderne, a 300.000 doza od CureVaca.[/size]
Pa stvarno im treba porazbijati glave
kaya- Posts : 31419
2015-08-15
Re: Južna Afrika: Oxfordsko cjepivo je na razini placeba
by Hartmann 8/2/2021, 21:07
Krasno netko eksperimentira sa populacijim zemaljskom.Kako sto vise osiromasiti sto vise stanovnika Zemlje,kako sto vise i duze produziti razlog uvodjenja morbidnih mjera.Ugostiteljstvo,jedno od cijenjenijih i tradicionalnijih nacina stjecanja zarade,u francuskoj,sve vise stradava.Mali su davno vec kljuc u bravu gurnuli,srednji zilave,veliki jos preko svojih veza u politici prezivljavaju
_________________
Hartmann- Posts : 1999
2021-01-04
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